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Product is suitable for Vegans No GMO For Diabetics 100 % Natural Product

High-performance fibrin-cleaving proteolytic enzyme. Excessive amounts of fibrin cause the blood to thicken and cause blood clots to form.

57.96 €

Product description

Nattokinase Plus contains the proteolytic enzyme nattokinase and inulin. Proteolytic enzymes work as organic catalysts (accelerators) to break down large molecules of proteins. When these proteolytic enzymes are taken with food, they promote the breakdown of dietary proteins up to amino acids that are easily absorbed by the digestive system. When used on an empty stomach, the enzymes are absorbed into the blood and circulated to the tissues, where they systematically exert their protein breakdown function2.

Fibrin is an insoluble protein formed during the final stage of blood clotting. It is found in blood vessels and the bloodstream. Blood cells are trapped in a web made of fibrin. With a large cobweb, clogging of the blood vessels can occur and subsequently the development of various cardiovascular diseases (thrombosis, myocardial infarction, stroke, pulmonary embolism)1.

The enzyme nattokinase is isolated from traditional Japanese fermented soybean Natto. Is natural and is obtained from the non-pathogenic bacterium Bacillus subtilis natto. Nattokinase is used in various countries in Asian countries and has been used in Japan for over 2,000 years. The proteolytic enzyme nattokinase is resistant to heat and stomach acids. The enzyme nattokinase contributes to better wound healing after injuries or operations3 and can improve blood circulation in the limbs4. It is also suitable to help reduce the risk of blood clots5.

The enzyme Nattokinase is a suitable alternative to the enzyme Serrapeptase.


  • NSK-SD ®nattocinase - extract from fermented soybeans, contains 100 mg of active substance in 1 herbal capsule. Under this label is a certified and pure form of nattokinase with a unique authorization for placing on the market within the EU. The enzymatic activity is 2000 FU (FU = (fibrinolytic unit) which is a unit of fibrin degradation.) The higher this FU value, the stronger the effect of protein degradation)1.
  • Inulin - a soluble fiber that acts as a prebiotic for probiotic cultures in the small intestine. It serves as food for its own good bacteria, which produce B vitamins and these improve the absorption of the enzyme through the wall of the small intestine, which makes maximum use of the enzyme by the body.


  1. Hsia et al., 2009. Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects. , 29(3), 0–196. doi:10.1016/j.nutres.2009.01.009 LINK
  1. Mamadou, 2012. Proteolytic Enzymes: A Novel Approach in Cardiovascular Dietary Supplementation. Phytomedic Labs LINK
  2. Zhang et al., 2017. Nattokinase Crude Extract Enhances Cutaneous Wound Healing. Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining, Shandong, P. R. China Key Laboratory of Laboratory Medicine of Jiangsu Province, School of Medicine, Jiangsu University, Zhenjiang, 212013, Jiangsu, P. R. China LINK
  1. Watanabe et al., 2019. Effect of nattokinase on the blood flow improvement in healthy subjects-a randomized, placebo-controlled, double-blind, cross-over study. Japanese pharmacology and therapeutics, 2018, 46(10), 1739‐1748 | added to CENTRAL: 31 March 2019 | 2019 Issue 3. LINK
  1. Weng et al. 2017. Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease. International Journal of Molecular Sciences, 18(3), 523–. doi:10.3390/ijms18030523. LINK
  1. Dabbagh et al. 2014. Nattokinase: production and application. Applied Microbiology and Biotechnology, 98(22), 9199–9206. doi:10.1007/s00253-014-6135-3 LINK

Product is suited for

  • For all people who want to take comprehensive care of their healthy vascular system
  • During long and frequent flights and the associated difficulties
  • For people who have an insufficient drinking regime
  • For people who have cold limbs
  • For athletes for faster regeneration6
  • Also for vegans

Recommended intake

1 capsule in the morning or evening on an empty stomach, 30 minutes before or 2 hours after a meal.

Serving instructions

Is necessary to swallow the capsules with a sufficient amount of water. Improper use of a nutritional supplement reduces its absorption and thus its effect.

Nutritional values

100 g1 capsule (400 mg)*GDA %
Energy value1041,8 kJ/249 kcal4,1672 kJ/0,996 kcal0,04
Proteins1,4 g0,0056 g0,011
Carbohydrates93,2 g0,37 g0,13
Fats0,025 g0 g0
Active substance: Natokináza100mg-

* GDA% - guideline daily amounts - percentage of daily value per serving. Reference intake of an average adult (8400 kJ / 2000 kcal).

** GDA% - not specified

Inulin, extract from fermented soybeans NSK-SD ® Nattokinase (100 mg), magnesium stearate, vegetable capsule.


Not suitable for children under 18 years of age, pregnant and breastfeeding women. Keep out of the reach of small children in a dry place at a temperature below 25 ° C. Do not expose to direct sunlight. Do not use as a substitute for a varied and balanced diet and a healthy lifestyle. The recommended daily dose should not be exceeded. People taking medicine should only consume the product under medical supervision.


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Frequently asked questions

Preventively when swelling, varicose veins, high blood pressure or other symptoms related to the cardiovascular system appear.

2000 FU (FU = fibrinolytic unit) is a unit of fibrin degradation and expresses the degree of enzymatic activity. The higher this FU value, the stronger the effect of thrombus degradation. Two thousand units can be found in 1 capsule.

Taking Nattokinase Plus to empty stomach increase the efficiency and absorption of enzymes.

When using other medicines, we recommend consulting a doctor and using the product under medical supervision.

The enzyme Nattokinase is a suitable alternative to the enzyme Serrapeptase.